This article applies to 123-reg VPS hosting running cPanel
This article will explain how you can set up an email auto responder using cPanel.
1
Login to cPanel customer interface.

2
Under the Mail section, click on the Auto Responders link.
3
Click on the Add Auto Responders button.
4
Fill out the Add Auto Responder form.
5
When complete, click the Create/Modify button.

Your new Auto Responder will now be created.